While the other treatment options resulted in better healing than the control group, this difference was not significant. Tensile stress was significantly improved in the Aloe vera gel group as compared with the other four groups (P≤0.05). To evaluate the efficacy of each treatment technique, a biomechanical approach was used to assess tensile stress after 14 days of treatment. In a randomized controlled trial, twelve male rats, aged 120 days and with a mean weight of 250 to 300 g, were divided randomly into 5 groups based on drug treatments: Aloe vera gel (AV), thyroid hormone cream (TC), silver sulfadiazine 1% (S), vehicle (V) and control. This study aimed at investigating the effects of topical application of an Aloe vera gel, a thyroid hormone cream and a silver sulfadiazine cream on the healing of skin wounds surgically induced in Wistar rats for determining the treatment of choice. However, the effects of these therapeutic agents are not well understood and have not been compared in one study. Many research studies report the healing effects of Aloe Vera, thyroid hormone cream and silver sulfadiazine. Norouzian, Mohsen Zarein-Dolab, Saeed Dadpay, Masoomeh Gazor, Roohollah Please discuss with the burns team if you are not happy to change the dressing yourself.A comparative study of the effects of topical application of Aloe vera, thyroid hormone and silver sulfadiazine on skin wounds in Wistar rats If you have any doubts, concerns or questions about how to use Flamazine™, please contact the burn team. Keep Flamazine™ in cool place and out of the reach of children. Please contact the Burns Team or attend the Emergency Department if unwell. If in doubt contact the Burns Team Stop using Flamazine™: The Burns team will advise you when to stop using Flamazine™. * If you using Flamazine™ on the genitalia reapply every time you go to the toilet/change nappy. Renew every 24 hours unless instructed otherwise.Reapply cream generously (3-5mm thick) and cover.Clean with the gauze provided using a wiping motion to ensure the old cream is removed.You can soak the affected area if possible. Mix 5mls (teaspoon) of the antiseptic soap provided spoonful into 200mls (about ½ a pint) of tap water.Remember to take analgesia before changing your dressings Give Flamazine™ to anyone else, even if they have similar problems to yours.If you suffer from: Glucose-6- phosphate deficient, low white cell count, problem with your liver or kidneys.If you are allergic to Silver Sulfadiazine or any other of the ingredients in Flamazine.If the tube is expired or has been opened for more than 7 days.It is soothing when applied and has proven activity against a broad range of organisms including both Gram-positive and Gram-negative bacteria and some viruses and fungi Don’t use Flamazine™: What is it used for?įLAMAZINE™ is used to prevent infection in severe burns and might be used to help removing burnt dead tissue. Flamazine cream for burns What is Flamazine™?įLAMAZINE™ is a topical antibacterial cream with an active ingredient which belongs to the group of antibiotic medicines called sulphonamides.įlamazine™ contains Silver Sulfadiazine.
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